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Pathogens and Their Antimicrobial Susceptibilities of Endodontic Infection in Type II Diabetes Mellitus Patients
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Á¶ÁÖ¿¬:Cho Ju-Yeon
±è¼º±³:Kim Sung-Kyo
KMID : 0362720160540050356
Abstract
Aim: The purpose of this study was to identify dominant pathogens and their antimicrobial susceptibilities of endodontic
infection in type II diabetes mellitus (DM) patients to determine effective empirical antibiotics.
Methodology: Pathogens from endodontic infection in six patients with DM and in six patients without DM were cultured,
identified and their antimicrobial susceptibility was tested using Vitek2 systems (bioMerieux, Marcy l¡¯ Etoile, France). The results were analyzed using Chi-square test and Fisher¡¯s exact test at P< 0.05 level.
Results: Pathogens of opportunistic infection were dominant in DM patients (P=0.015). However, there was no significant difference of antimicrobial susceptibility between DM and non-DM patients. Relatively high percent (27%) of pathogens showed resistance to penicillin.
Conclusions: More cautions should be paid to DM patients because they are prone to opportunistic infection. Penicillin is not effective in the control of endodontic infection.
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Diabetes mellitus; Pathogen; Endodontic; Infection
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